transglutaminase 1

TRANSGLUTAMINASE 1 (TGM1 or TGK) is a membrane-associated enzyme involved in the formation of the cornified cell envelope of the EPIDERMIS; Mutations in the human gene (14q11) cause autosomal recessive lamellar ICHTHYOSIS; Distinguish from GAMMA-GLUTAMYLTRANSPEPTIDASE involved with glutathione metabolism and other protein cross-linking transglutaminase; RefSeq NM_019984 (mouse), NM_031659 (rat), NM_000359 (human)

Also Known As:

TGASE, human; TGK protein, human; TGM1 protein; TGM1 protein, human; TGase 1, mouse; Tgm1 protein, mouse; Tgm1 protein, rat; epidermal type I transglutaminase; keratinocyte transglutaminase K; transglutaminase 1 (K polypeptide epidermal type I, protein- glutamine- gamma- glutamyltransferase), human; transglutaminase 1, K polypeptide, mouse; transglutaminase 1, rat; transglutaminase K; transglutaminase TGM1; transglutaminase Type I; transglutaminase i; transglutaminase1

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Transferases: 6589
    - Acyltransferases: 374
      - Aminoacyltransferases
        Transglutaminases: 1050
        transglutaminase 1: 99

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Drug/Important Bio-Agent (IBA)